Effects of honeybee (Apis mellifera) venom on keratinocyte migration in vitro

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Effects of honeybee (Apis mellifera) venom on keratinocyte migration in vitro

BACKGROUND Since the ancient times the skin aging application of honeybee venom (BV) is practiced and persisted until nowadays. The present study evaluated the effect of the honeybee venom (BV) on keratinocyte migration in wound healing model in vitro. OBJECTIVE To access BV further as a cosmetic ingredient and a potential external application for topical uses, we performed studies to investi...

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Hyperalgesic and edematogenic effects of Secapin-2, a peptide isolated from Africanized honeybee (Apis mellifera) venom

Honeybee stings are a severe public health problem. Bee venom contains a series of active components, including enzymes, peptides, and biogenic amines. The local reactions observed after envenoming include a typical inflammatory response and pain. Honeybee venom contains some well-known polycationic peptides, such as Melittin, Apamin, MCD peptide, Cardiopep, and Tertiapin. Secapin in honeybee v...

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Thermal learning in the honeybee, Apis mellifera.

Honeybee foragers are exposed to thermal stimuli when collecting food outside and receiving food rewards inside the nest. In both contexts, there is an opportunity for foragers to associate warmth with food rewards. However, honeybee thermal learning is poorly understood. Using an associative learning paradigm (the proboscis extension reflex), we show that honeybees can learn to associate a nec...

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Resonance frequencies of honeybee (Apis mellifera) wings.

During flight, insect wings bend and twist under the influence of aerodynamic and inertial forces. We tested whether wing resonance of honeybees (Apis mellifera) matches the wingbeat frequency, against the 'stiff element' hypothesis that the wing's first longitudinal mode exceeds the wingbeat frequency. Six bees were immobilized with their right wing pair outspread, and stimulated with a shaker...

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Evaluation of Anticancer Effects Induced by Apis mellifera Venom on Breast Cancer Cell Line

Background: In recent years, the number of people with cancer has increased. For this reason, different drugs have been suggested for the treatment of cancer, but none of them has resulted in complete remission. Many bio-toxins are biologically active compounds with anticancer activity. In the meantime, bee venom (BV) has a potent anti cancer and tumor effects. The aim of present study is evalu...

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ژورنال

عنوان ژورنال: Pharmacognosy Magazine

سال: 2013

ISSN: 0973-1296

DOI: 10.4103/0973-1296.113271